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br Experimental procedure br Results and discussions Lombard
2020-08-05
Experimental procedure Results and discussions Lombardi plate cohesion, mini slump flow diameter and marsh cone flow time of grout samples are shown in Table 2. Moreover the rheological properties including plastic viscosity and yield stress of grout samples are listed in Table 3. The correlat
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The IL family of cytokines actually comprises
2020-08-05
The IL-6 family of cytokines actually comprises nine members, such as leukemia inhibitory factor (LIF) and oncostatin M (OSM). All IL-6–type cytokines share the signal-transducing receptor subunit gp130 (or gp130 like), and receptor specificity is provided by additional receptor chains. IL-6 first b
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Third DGK protein stabilization by myristic acid
2020-08-04
Third, DGKδ2 protein stabilization by myristic Cholera Toxin is cell line specific. Myristic acid had no obvious effects on DGKδ protein stability in the liver cell line HepG2, pancreas cell line MIA-PaCa-2 and neuronal cell line Neuro-2a cells (Fig. 5). Although myristic acid moderately increased
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terbinafine hydrochloride br Conflicts of interest br Acknow
2020-08-04
Conflicts of interest Acknowledgments This study was supported by the Beijing Natural Science Foundation (No.7192015), the Great Wall scholars program of Beijing Municipal Education Commission (No.CIT&TCD20180308) and Beijing Municipal Commission of Education Research Projects (Grant No. KM201
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br Results br Discussion The Ube E
2020-08-04
Results Discussion The Ube2E group of ubiquitin-conjugating enzymes, classified as the Class III E2s owing to their N-terminal extensions, is considered as “hub” E2s due to their capability of interacting with a large number of E3 ligases [26], [33]. The “E3 interactome” of these E2s is second
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In addition to supporting the catalytic function of
2020-08-04
In addition to supporting the catalytic function of BRCC36, KIAA0157 and Abraxas also serve scaffolding functions to recruit the BRCC45–MERIT40 heterodimer and the targeting subunits RAP80 or SHMT2. Surprisingly, super dimerization is not only required for the catalytic function of BRCC36 but it is
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On the other hand the
2020-08-03
On the other hand, the IL-8 promoter activity induced by the signalling cascade of the CysLT1-G300S receptor is higher than that of the WT receptor. The chemokine IL-8 is mainly involved in the recruitment and activation of neutrophils and we have previously shown that this chemokine gene is a targe
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br Materials and methods br Results br
2020-08-03
Materials and methods Results Discussion The role of pro-inflammatory pathways linked to the ubiquitin-proteasome system in the pathogenesis of atherosclerosis is an emerging area of investigation. Indeed, studies demonstrate putative roles of proteasomal blockade, protective effects of ubi
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niclosamide mg The RING finger and the U box type E
2020-08-03
The RING-finger and the U-box- type E3 ligases act as a scaffold protein to bridge an E2 enzyme and a substrate proximally for ubiquitin conjugation (Fig. 1). The RING-finger-type E3 ligases are generally thought to be the biggest family of ligases and contain a Zn2+-coordinating domain with spaced
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Curcumin Phosvitin PV is a highly phosphorylated protein fro
2020-08-03
Phosvitin (PV) is a highly phosphorylated protein from egg yolk (Byrne et al., 1984). Phosvitin and its derived phosvitin hydrolysate (PVH) were reported to exert various physiological activities such as anti-inflammatory activity (Hu et al., 2013, Xu et al., 2012, Young et al., 2011), antioxidant a
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E protein was studied using specific anti E antibodies
2020-08-03
E1 protein was studied using specific anti-E1 ap-1 transcription factor in wild type cells and in transfected cells overexpressing the enzyme. The results revealed several unusual characteristics, which are unique to this ubiquitin-activating enzyme. The E1 was translated as a full-length protein an
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br Declaration of interest br Author contributions
2020-08-03
Declaration of interest Author contributions Acknowledgement This study was supported by a Grant-in-aid for Scientific Research from The Ministry of Education, Culture, Sports, Science, and Technology of Japan (No. 26670733 and No. 26293363 to K. Miyado). Introduction Lead (Pb) is an im
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Building s constructional elements should be able to protect
2020-08-03
Building\'s constructional elements should be able to protect residents from the negative effect of noise caused by surroundings [19]. The World Health Organization estimates that each year more than one million Healthy Life Years are lost in the European Union member states and other Western Europe
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It is well known that
2020-08-03
It is well known that vascular NO is produced by eNOS by converting l-arginine to l-citrulline in the presence of molecular oxygen [8]. Tetrahydrobiopterin (BH4) is an essential cofactor of eNOS that aids in the coupling of l-arginine and the heme group within the oxygenase domain of eNOS. In this c
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Introduction In vitro synthetic biology has received conside
2020-08-03
Introduction In vitro synthetic biology has received considerably less attention than in vivo processes so far (Foster and Church, 2007). However, cell-free biosynthetic production is very likely to become important for many biotechnological challenges for reasons such as (energy) efficiency, syste
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