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Based on the deduced amino acid sequence of
2021-05-13
Based on the deduced amino phenylephrine hydrochloride mg sequence of the catalytic subunit of rG3DH, we could find sequence features that are highly conserved in FAD-harboring dehydrogenase, which include FAD binding motif and sequential cysteine residues in Cysteine-rich region. Several dehydroge
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Many filarial species harbor an
2021-05-13
Many filarial species harbor an endosymbiotic bacterium of the genus Wolbachia. A recent investigation of Wolbachia distribution in 35 filarial species including 28 species and 7 genera and/or subgenera have shown that 37% of them harbor Wolbachia (Ferri et al., 2011). In filarial nematodes, Wolbach
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MTT results show that both
2021-05-13
MTT results show that, both pancreatic cell lines were quite sensitive to camptothecin (CPT), a well known topoisomerase I poison. Interestingly, CPT does not show any selectivity over cancer cell lines probably due to the duplication times for cancerous (MIA PaCa-2) and immortalized healthy (HPDEC)
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There are two general approaches to
2021-05-13
There are two general approaches to building Bayesian networks for the purpose of risk assessment. Researchers can implement static models that predict risk or survival at a snap-shot of time. For example, Loghmanpour et al. [10] created Bayesian network-based risk assessment models for patient data
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WM refers to the storage
2021-05-13
WM refers to the storage of information in the context of processing, and coordination of elements into new structures (Oberauer, Süß, Wilhelm, & Wittman, 2003). Concerning the impact of WM on ISV facets, a strong negative association between WM and ex-Gaussian tau, suggesting that improved WM perf
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The aim of the present study was to investigate
2021-05-13
The aim of the present study was to investigate the acute effects of THC on resting state dofetilide neurophysiology, and to examine the impact of COMT genotype on these effects. Thirty-nine healthy volunteers participated in a randomised, placebo-controlled, crossover pharmacological MRI study. Ac
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Materials and methods br Results br Discussion Microbial pro
2021-05-13
Materials and methods Results Discussion Microbial production of trans-4Hyp, an added-value amino Bromosporine for pharmaceuticals, offers significant advantages over conventional chemical extraction in economic and environmental aspects. However the low titer and productivity with the exist
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The present study intended to characterize the
2021-05-13
The present study intended to characterize the predominant cholinesterasic form found in tissues of three tropical fish species, namely Phalloceros harpagos Lucinda, 2008 (common name guaru), Pterygoplichthys pardalis Castelnau, 1855 (common name cascudo) and Astyanax altiparanae Garutti and Britski
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To identify and characterize new possible molecular targets
2021-05-12
To identify and characterize new possible molecular targets, the mechanisms of various kinds of TCDD toxicities that occur by abnormal regulation in the downstream of AhR signals have been studied (Yoshioka et al., 2011). Experimental evidence has revealed that prostanoids (i.e., prostaglandins and
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Enzyme mimics belong to a
2021-05-12
Enzyme mimics belong to a type of rising catalysts which show the similar function with their corresponding natural enzymes [20], [21], [22], [23], [24], [25], [26], [27], although their structures are different from natural enzymes. In the area of prodrug activation, the widely-used enzyme mimics a
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br Regulation of cadherin switching The downregulation of
2021-05-12
Regulation of cadherin switching The downregulation of E-cadherin during cadherin switching is induced by multiple mechanisms, including methylation of the E-cadherin promoter and signaling pathways that activate E-cadherin-suppressing transcription factors [[61], [62], [63]]. During the progress
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Chemokine receptor expression in MCL
2021-05-12
Chemokine receptor expression in MCL is shown in Table 1. CXCR4, CXCR5 and CCR6 protein was detected in the majority of patients [10], [72], [102], [118] and CX3CR1 was found to be present in up to 75% of cases depending on the method used to identify the receptor [103]. CCR7 was more highly express
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br Oxysterols as Key Players in Metabolic Syndrome Obesity a
2021-05-12
Oxysterols as Key Players in Metabolic Syndrome? Obesity and sedentary lifestyle are on the rise and pose serious threats to people's health and wellbeing. Obesity is often associated with other pathologies and is one of the criteria included in the definition of metabolic syndrome (MetS) (see Gl
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NMDA australia Collectively our results indicate that GSK A
2021-05-12
Collectively, our results indicate that GSK682753A functions as a competitive antagonist and binds to the receptor in the same region as 7α,25-OHC. First, we observe linearity in the Schild plot analysis (Fig. 2B). Second, GSK682753A is highly dependent on F111 at position III:08/3.32 in TM-III (Fig
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br Results and Discussion br Conclusions
2021-05-12
Results and Discussion Conclusions Understanding the connections between function and fitness is a primary goal of many biological disciplines including systems biology and molecular evolution. While sound approaches have been developed to understand the connections between function and fitnes
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