• br Materials and methods br Results The clinical

  2023-08-11

  

  Materials and methods Results The clinical characteristics of the two selected groups are shown in Table 1. As shown in Table 1, the enzyme activity of ATX in CSF of MS patients (59.90±3.09nmol/min/ml±SEM) was significantly higher (p find a strong association between ATX activity and MS, we co

• To investigate if WP increased

  2023-08-10

  

  To investigate if WP increased CAT activity in cells, C2C12 muscle am 630 were treated with 0.1 to 0.4 mg/mL of WP (80.05% protein) for 24 h and then stressed with 0.75 mM H2O2 for 1 h (Xu et al., 2011). The CAT activity was significantly enhanced from 15.1 ± 0.7 to 23.7 ± 1.3 U/mg of total cellula

• A has been reported to decrease insulin receptors and impair

  2023-08-10

  

  Aβ has been reported to decrease insulin receptors and impair insulin signaling in neurons, preventing phosphorylation of Akt and glycogen synthase kinase 3β (GSK-3β), downstream of insulin signaling, and to increase phosphorylation of tau protein causing neurofibrillary tangles (Tokutake et al., 20

• br Serine glycine and one

  2023-08-10

  

  Serine/glycine and one-carbon metabolism Altered serine metabolism in tumors was noted nearly half a century ago, and elevated flux through the de novo serine synthesis pathway (SSP) is a common phenomenon in cancer Ac-IETD-pNA [43]. The SSP branches from glycolysis at the point of 3-phosphoglyc

• As the close paralog of adiponectin

  2023-08-10

  

  As the close paralog of adiponectin, we hypothesized that CTRP9 could participate in regulation of reproduction. In order to evaluate whether Ctrp9 plays a role in the control of reproduction in tilapia, i.p. injection experiment was performed. HPG (Hypothalamic/pituitary/gonadal) axis plays a key r

• Introduction Preeclampsia a serious hypertensive disorder th

  2023-08-09

  

  Introduction Preeclampsia, a serious hypertensive disorder that can occur during pregnancy, is a pregnancy-related disease characterized by the onset of Clofibric Acid and proteinuria after the 20 t h week of gestation, and it occurs in about 5% of all pregnancies [1]. If left untreated, preeclamps

• Among steroid saponins ginsenosides are

  2023-08-09

  

  Among steroid saponins, ginsenosides are the active components of ginseng, a well-known chinese medicinal plant. More than hundreds of different ginsenosides have been isolated from ginseng and have shown in the past to be membrane active substances and to influence the membrane by modulating lipid

• Over the years measures of total antioxidant status TAS

  2023-08-09

  

  Over the years, measures of total antioxidant status (TAS) have been developed to capture the collective effect of antioxidant defense capacity, including enzymatic and nonenzymatic systems (Fraga et al., 2014, Franco et al., 2007). Multiple antioxidant enzymes, as well as antioxidant vitamins and m

• br Conclusions br Declarations br Introduction

  2023-08-09

  

  Conclusions Declarations Introduction The classical term of endocrine disruption includes any agent that interferes with the action of hormones within the human body; these agents are therefore named endocrine disruptors. Among these agents, that are mainly environmental chemicals (pollutan

• br Identification of the croaker mAR cDNA

  2023-08-09

  

  Identification of the croaker mAR cDNA Testosterone (T) was observed to alter steroidogenesis through a nongenomic mechanism (not blocked by the transcription inhibitor, actinomycin D) in Atlantic croaker ovarian tissues (Braun and Thomas, 2003). This action of T was mimicked by T conjugated to B

• br Concluding Remarks and Future Perspectives While postmort

  2023-08-09

  

  Concluding Remarks and Future Perspectives While postmortem human GSK 650394 material is relatively sparse and has inherent limitations as discussed above, additional investigations could benefit from analysis of in vitro cellular models to corroborate findings in patient material. Generation of

• br AR signals and chemosensitivity in

  2023-08-08

  

  AR signals and chemosensitivity in urothelial cancer A significant amount of patients with urothelial cancer fail to respond to cisplatin-based systemic chemotherapy, although it remains the mainstay of successful management of advanced disease. However, underlying mechanisms for chemoresistance

• It has been reported that trehalose shows beneficial effects

  2023-08-08

  

  It has been reported that trehalose shows beneficial effects in a mouse model of several neurodegenerative diseases [21], [22], [23]. There are also reports showing that trehalose can improve the impaired cognitive and learning ability and reduced Aβ deposit in hippocampus of APP/PS1 transgenic mice

• br Funding This study was supported by

  2023-08-08

  

  Funding This study was supported by a grant from the Science and Technology Program of Guangzhou (No. 2014Y2-00181) and the personnel training program of Southern Medical University (No. PY2015N023). Conflict of interest statement Authors’contributions Introduction Chronic cerebral hypo

• sik inhibitor br Materials and methods br Results Table pres

  2023-08-08

  

  Materials and methods Results Table 1 presents the metabolic phenotype of obese minipigs. After 60 d of HFHS feeding, minipigs not only showed an increased body weight (+45%), but also a perturbed sik inhibitor homeostasis, with higher insulin levels (about +2-fold), HOMA-IR (+5.5-fold), and H

15751 records 263/1051 page Previous Next First page 上5页 261262263264265 下5页 Last page