br Experimental Procedures br Author

2018-10-20

Experimental Procedures Author Contributions Acknowledgments Introduction Since their discovery and isolation in 1998, human embryonic stem Tozadenant (hESCs) have been considered a potentially valuable tool for generating replacement cells for therapeutic purposes (Lanza et al., 2009).

a01 The neurogenic to gliogenic transition of NSPCs

2018-10-20

The neurogenic-to-gliogenic transition of NSPCs is probably governed by a multi-layered system. The epigenetic status of astrocyte-specific (Takizawa et al., 2001) and neurogenic genes changes during development (Hirabayashi et al., 2009; Kishi et al., 2012; Pereira et al., 2010), critically determi

Engraftment repopulation of the satellite niche and response

2018-10-20

Engraftment, repopulation of the satellite niche, and response to additional injury clearly demonstrate that the human CD56+/CD29+ satellite cell population contains muscle stem cells. With respect to engraftment, our experiments resulted in a greater efficiency of human-derived fiber generation (Fi

At the molecular level cell fate is

2018-10-20

At the molecular level, cell fate is controlled by epigenetic mechanisms that modulate GDC-0941 structure and thereby control utilization of genetic information (Boland et al., 2014; Meissner, 2010). Changes in chromatin structure are, in part, induced by specific post-translational modifications of

The particular anatomy of the olfactory and

2018-10-20

The particular anatomy of the olfactory and trigeminal neural pathways connects the nasal mucosa directly with the order EPZ-6438 and the perivascular pathway by circumventing the BBB (Jiang et al., 2015). Using intranasal delivery, several therapeutic agents, such as small molecules, proteins, hor

Hello world!

2018-07-29