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In this issue of EBioMedicine Enroth and colleagues present
2018-11-07
In this issue of EBioMedicine, Enroth and colleagues () present a comprehensive study that analyzes the individual contribution of factors related to the collection and long-term sample storage in a highly homogenous group of Northern European subjects (). Taking advantage of the sampling strategy o
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order substance p In agreement with other studies Stein et a
2018-11-07
In agreement with other studies (Stein et al., 2009; Zhang et al., 2015; Lee et al., 2015) serum levels of the FGF-21 depend on renal functions because renal elimination is a major route by which physiological FGF-21 serum levels are maintained. Like other researches (Stein et al., 2009; Lee et al.,
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Munc proteins are known to facilitate formation of trans
2018-11-07
Munc18 proteins are known to facilitate formation of trans-SNARE complexes that mediate SG fusion (Sudhof and Rothman, 2009). β-cells express all three Munc18 isoforms, Munc18a, b, and c (Oh et al., 2012; Lam et al., 2013; Zhu et al., 2015). We recently reported Munc18c/Syn-4 complex\'s role in insu
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We first confirmed PDLIM overexpression in primary meningiom
2018-11-07
We first confirmed PDLIM2 overexpression in primary meningioma and schwannoma samples and showed that it is not expressed in HMC or normal meningeal tissue and minimally expressed in the Schwann cell examined. PDLIM2 was significantly knocked down in three primary meningioma and three primary schwan
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Alpha and beta tubulin are palmitoylated Caron and Herwood C
2018-11-07
Alpha and beta-tubulin are palmitoylated (Caron and Herwood, 2007; Caron et al., 2001; Zambito and Wolff, 1997; Ozols and Caron, 1997; Caron, 1997), and tubulin palmitoylation helps to anchor microtubule filaments in the plasma membrane and supports functions needed for cellular transport and divisi
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The findings of Liang and co workers add to current
2018-11-07
The findings of Liang and co-workers add to current knowledge on gastric and colorectal carcinogenesis, uncovering the cooperation between deranged genetic and epigenetic mechanism in two extensively studied tumor models. In addition, novel CRC prognostic biomarkers might allow for improved patient
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br Conflict of Interest Statement br
2018-11-07
Conflict of Interest Statement Search Strategy and Selection Criteria Data for this review were identified by searches of PubMed, using the following search terms in various combinations: “NFIB”, “cancer”, “development”, “cellular differentiation”, “NFI transcription factors”. Articles resulti
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Dried fractions were reconstituted in acetonitrile
2018-11-07
Dried fractions were reconstituted in 10% acetonitrile (100μl) and injected (20μl) onto an Aeris PEPTIDE XB-C18 100×2.1mm column, with solid core 1.7μm particles (100Å) (Phenomenex, Torrance, CA). RP-LC was performed (300μl/min, 40°C) on a Nexera UHPLC system (Shimadzu, Columbia, MD) with water (A)
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Value of the data br Data experimental
2018-11-07
Value of the data Data, experimental design, materials and methods Acknowledgments This work was financially supported by the grant sponsors: Shenzhen Municipal Committee of Science and Technology Innovation (Grant number: JC201105190969A) and the National Public Sector (AQSIQ) Special Funds
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br Acknowledgments We would like to
2018-11-07
Acknowledgments We would like to thank Dr. Daniel Conrad and Julie Farnsworth at the Flow Cytometry Research Core at the Massey Cancer Center, VCU. This project was funded by the National Institute of Justice Award number 2013-DN-BX-K033. Data Experimental design, materials and methods A
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rxr receptor Further we sort the lipids into annular and
2018-11-07
Further, we sort the rxr receptor into annular and non-annual regions (Fig. 12). Finally, we plot the lipid-number mismatch and surface area per lipid mismatch of several asymmetric lipid membrane systems (Fig. 13). The design of the initial structures (Fig. 8) of the dimer protein and lipid bilaye
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The following materials and methods section will enable
2018-11-07
The following materials and methods section will enable other investigators and laboratories to design similar experimental procedures to study matrix metalloproteinases or any other protease by PICS proteomics. Please refer to our recent dental pulp proteomics and N-terminomics Data in Brief articl
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The discount rates and factors
2018-11-07
The discount rates and factors reported in this paper are derived based on an estimation of the Cox-Ingersoll-Ross (CIR) stochastic interest rate model [1]. The data can then be used to evaluate investment projects, even when their cash flows occur in the distant future. In the CIR model, the dynam
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Statistical analyses were done using the SAS
2018-11-07
Statistical analyses were done using the SAS procedure PROC FREQ for Fisher׳s exact test, PROC MIXED for ANOVA followed by Dunnett׳s test, PROC GENMOD for GEE (SAS version 9.3, SAS Institute, Cary, NC, USA) and R version 3.2.5 scmamp package for Rom [5] adjusted p-value. The supplemental files to th
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The anatomical differences found between the Chinese and
2018-11-07
The anatomical differences found between the Chinese and U.S. child templates parallel the findings of secretin receptor differences between these two developmental populations from previous research. For example, Guo et al. (2007) found different trajectory of GM development between Chinese and U.S
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