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nrf2 inhibitor br Short case report A year old man with
2019-04-15
Short case report A 65-year-old man with persistent AF underwent multi-detector computed tomography (CT) before catheter ablation. An anomalous muscular band connecting the posterior side of the left atrial roof and the right edge of fossa ovalis in the left atrium was detected (Fig. 1). During
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br Discussion Compared to the right ventricular outflow trac
2019-04-15
Discussion Compared to the right ventricular outflow tract, the LVOT has a more complicated anatomic structure, comprising the mitral annulus, aortic cusps, and LV basal myocardium. The AMC bridges the aortic and mitral valves with fibrous tissue, called the left fibrous trigone [3], and the exte
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s6 kinase br In Sanguinetti et al and Barhanin
2019-04-15
In 1996, Sanguinetti et al. and Barhanin et al. independently found that, when coassembled with the accessory subunit KCNE1, the KCNQ1 and KCNE1 complex could form a channel that very closely exhibited conductive and kinetic properties similar to that of cardiac IKs[14,56]. Kass and coworkers subs
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The most compelling apparent evidence in support of
2019-04-15
The most compelling apparent evidence in support of the depolarization hypothesis derives from the seminal studies of Nademanee et al. [129]. showing that radiofrequency ablation (RFA) of epicardial sites displaying late potentials and fractionated bipolar electrograms in the RVOT of patients with B
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br Discovery of S PR as
2019-04-15
Discovery of S1PR2 as a CBA sensor in the liver Early studies reported that activation of the ERK1/2 and AKT signaling pathways by CBAs was PTX-sensitive, suggesting a role for a Gαi-linked GPCR. To identify which GPCR activates the ERK1/2 and AKT signaling pathways, the cDNAs encoding more than
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This Ca overload activates the forward mode
2019-04-11
This Ca2+ overload activates the forward mode of the Na+/Ca+ exchanger (NCX), increases the transient inward current (Iti), and induces ventricular arrhythmias due to delayed after depolarizations (DADs). Subtypes of CPVT Several subtypes of CPVT have been reported (Table 1). The most common typ
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Because our patient s native rhythm remained AV block
2019-04-11
Because our patient׳s native rhythm remained 2:1 AV block with a narrow QRS, we attempted HBP as the first-line treatment based on the assumption that His-Purkinje conduction might be preserved. Another benefit of HBP in this patient with CKD is that the use of iodinated ganciclovir media could be
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The excellent birth cohort study reported in by Heather
2019-04-11
The excellent birth cohort study reported in by Heather Zar and colleagues, done in a periurban area outside Cape Town in South Africa, is a good example of a study that has provided important information about child pneumonia at a time of change. It provides the first incidence estimates of pneumo
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br Introduction Narcolepsy is a
2018-11-15
Introduction Narcolepsy is a chronic disturbance that leaves patients incapacitated in most cases; it is characterized by an abnormal sleep pattern that may include excessive daytime sleepiness, sleep architecture alterations, and rapid eye movement (REM) sleep pathological manifestations, inclu
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En este escenario global M xico tiene ante s
2018-11-15
En este escenario global, México tiene ante sí el reto histórico de trascender su condición de país atrasado en el concierto internacional, y que ante la fallida estrategia de industrialización por sustitución de importaciones, lo llevó a integrarse a través del tlcan en los eslabones bajo y medio d
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The response variable of the models is
2018-11-15
The response variable of the models is binary, defined by the occurrence of at least one type of crime analyzed over the sirtuin covered by the victimization surveys (victim). It assumes value 1 if the individual i was victimized and 0 otherwise. Given this characteristic of the dependent variable,
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Similarly to Table the results
2018-11-15
Similarly to Table 4, the results from Table 5 showed a positive relation between the distribution of the exportation (EXP) and the distribution of the AD cases initiated by Turkey, European Union, South Korea, India and United States. Therefore, these economies would be favoring the most competitiv
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br Introduction The burden of malaria currently estimated at
2018-11-15
Introduction The burden of malaria, currently estimated at over 2 million episodes of clinical disease and 655,000 deaths annually (WHO, 2012), has exerted strong selection on the human genome, leading to the occurrence at high frequencies of a number of host-protective polymorphisms (Kwiatkowski
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It is important to recognize however that
2018-11-15
It is important to recognize, however, that documenting the presence of SES-associated neural effects alone is not sufficient to support this formulation. While lower-SES children may be deprived of certain enriching experiences, they may also have other experiences which are less often considered.
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History of the disease Nosology classification and diagnosis
2018-11-15
History of the disease: Nosology/classification, and diagnosis Evolution of concepts on causality The concept that medications were a frequent, if not the only, cause of TEN was rapidly accepted by the medical BLZ945 … may be too quickly in the opinion of Lyell. Strong evidence of such causalit
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